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12/9/2008

Affymetrix Technology Powers Cincinnati Children's Hospital's Innovative Test for Jaundice

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Plant and Animal Genome XVII Conference

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GeneChip® Human Mitochondrial
Resequencing Array 2.0

Analysis of mitochondrial mutations is informative for a variety of applications from disease genetics to forensic identification. The GeneChip® Human Mitochondrial Resequencing Array 2.0 provides the most efficient and cost-effective method for detecting germ line and heteroplasmic mutations by delivering the complete mitochondrial genome with minimal PCR in only 48 hours.

Features and Benefits

  • More Information Per Experiment
    The Human Mitochondrial Resequencing Array 2.0 interrogates the entire 16 kb genome on a single array.
  • Less PCR
    The robust Mitochondrial Resequencing Assay amplifies the entire genome in only three PCR reactions.
  • No Assembly Required
    The Mitochondrial Resequencing Array 2.0 delivers completed sequence in 48 hours with minimal alignment.

Array Specifications and Components

Format 169
Sequence Capacity 16kb
Feature Size 8 µm
Instrumentation GeneChip® Scanner 3000
Software Support GeneChip® Operating Software (GCOS)
GeneChip® Sequence Analysis Software (GSEQ)
Reagents GeneChip® Resequencing Reagent Kit

References

  • High-throughput variation detection and genotyping using microarrays.
    D.J. Cutler, et al. Genome Res 11(11): 1913-25 (2001).

  • New developments in high throughput resequencing and variation detection using high-density microarrays.
    J.A. Warrington, et al. Hum Mutat 19: 402-9 (2002).

  • The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection.
    A. Maitra, et al. Genome Research 14(5): 812-9 (2004).

  • Genomic Alterations in Cultured Human Embryonic Stem Cells
    A. Maitra, et al. Nature Genetics Epub (2005 Sep 4).

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Part # Description Details
900886 GeneChip® Human Mitochondrial Resequencing Array 2.0 5 Arrays
900447 GeneChip® Resequencing Reagent Kit 30 Reaction Kit

Related Products

Part # Description Details
GeneChip® Operating Software Available Via Download
GeneChip® Sequence Analysis Software Available Via Download