News and Events
12/9/2008
Affymetrix Technology Powers Cincinnati Children's Hospital's Innovative Test for Jaundice
12/8/2008
Affymetrix Completes Acquisition of Panomics

Plant and Animal Genome XVII Conference
1/10/2009-1/14/2009
Achieving ROI in Personalized Medicine: Barriers, Incentives, and Pathways to Commercialization
1/27/2009-1/28/2009
Scientific Publications
The Affymetrix GeneChip® Human (Panels 1 & 2) 20K cSNP Kit contains 20,000 amino acid-changing SNPs that are multiplexed in a single assay. It includes validated non-synonymous public SNPs that code for functional changes in more than 10,000 genes. It allows researchers to perform hypothesis-driven association studies for the direct detection of non-synonymous SNPs with links to biological pathways and gene function. The Human (Panels 1 and 2) 20K cSNP Kit data are generated using proven molecular inversion probe (MIP) technology in combination with Affymetrix Universal Tag Arrays, and scanned on an GeneChip® Scanner 3000 TG System.
Literature
Smyth D. J., et al. A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nature Genetics 38(6):617-619 (2006).
Zanke B. W., et al. Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nature Genetics 39(8):pp989-94 (2007).
Additional Materials
Brochures
Data Sheets
GeneChip® Human Panel 1 & 2, 20K cSNP Kit (pdf, 181 KB)
White Papers
Targeted Genotyping Algorithm Enhancements for Release 1.5 (pdf, 21 KB)
| Part # | Description | Details |
|---|---|---|
| 900827 | GeneChip® Human (Panels 1 & 2) 20K cSNP Kit | Kit contains enough reagents to process a total of 24 assays (23 customer samples and one kit control) |
| 901185 | GeneChip® Universal 25K Tag Array 24 Pack | Each pack contains 24 arrays, enough to process one Human (Panels 1 & 2) 20K cSNP Kit |
Related Products
| Part # | Description | Details |
|---|---|---|
| 000534 | GeneChip® Human (Panels 1 & 2) 20K cSNP Service | For more information on pricing, minimum number of samples or a list of third-party service providers, please consult the Affymetrix Services Home Page. |
Assay Panel Files
Human (Panels 1 & 2) 20K cSNP Kit (zip, 481 KB)
Manuals
Targeted Genotyping Analysis (GTGS) User's Guide, includes TG protocol (pdf, 1.9 MB)
Targeted Genotyping System Site Preparation Guide (pdf, 892 KB)
Targeted Genotyping System User's Guide (pdf, 4.04 MB)
Quick Reference Cards
Targeted Genotyping Quick Reference Card, includes TG Protocol (zip, 1.62 MB)
User Bulletin, Affymetrix Targeted Genotyping System (pdf, 69 KB)
Material Safety Data Sheets
Human (Panels 1 and 2) 20K cSNP Kit (pdf, 96 KB)
Targeted Genotyping Wash Solution A (pdf, 26 KB)
Targeted Genotyping Wash Solution B (pdf, 26 KB)
Additional Support
Custom Panel Design Guide (zip, 143KB)
Custom Panel Design Request Form (zip, 12 KB)



