GeneChip® 3' Expression Arrays

Industry-standard Expression Profiling with GeneChip® 3' Arrays

GeneChip® 3' expression arrays are the most broadly accepted whole-genome expression profiling tool. Affymetrix offers the largest collection of whole-genome catalog arrays, from Arabidopsis to zebrafish. With more publications than any other microarray platform and a wealth of functional annotation, Affymetrix 3' expression array users have an unprecedented resource to compare and refine results.

Affymetrix 3' expression arrays interrogate each gene with multiple independent probes, offering the most accurate, robust and reproducible 3'-based, gene-level expression profiling. Examine expression profiling on a genome-wide scale with the industry-standard platform. Available in single-array, 24-Array plate, and 96-array plate formats to meet your study needs.

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With over 11,000 publications using or reviewing Affymetrix expression products, Affymetrix has become the industry-standard microarray platform. This figure illustrates the number of gene expression publications (Affymetrix versus its major competitor) for core research areas.
Figure 1
With over 11,000 publications using or reviewing Affymetrix expression products, Affymetrix has become the industry-standard microarray platform. This figure illustrates the number of gene expression publications (Affymetrix versus its major competitor) for core research areas.

GeneChip® 3' expression arrays interrogate each gene with multiple independent probes, offering the most accurate, robust and reproducible 3'-based, gene-level expression profiling. With upwards of 11,000 publications using or reviewing our expression technology, GeneChip® arrays have become the industry-standard whole-genome expression profiling tool. Affymetrix' 3' expression portfolio includes whole-genome catalog arrays from Arabidopsis to zebra fish. Current solutions for human, mouse and rat include:

Affymetrix Expression Console Software

Expression Console™ software supports probe set summarization and CHP file generation for GeneChip® 3' expression arrays, as well as GeneChip® Gene and Exon Arrays. The Expression Console workflow provides a choice of the more commonly used probe set summarization algorithms. The algorithms offered include:

  • MAS5 Statistical Algorithm
  • Probe Logarithmic Intensity Error Estimation (PLIER)
  • Robust Multichip Analysis (RMA)

GeneChip-Compatible™ Software

For advanced secondary analysis, several GeneChip-Compatible™ software packages are available.

Gene Expression Signature Defines Burkitt's Lymphoma

Christian-Albrechts University's Reiner Siebert, Charité-Universitätsmedizin Berlin's Michael Hummel and Universidad de Cartagena's Niradiz Reyes discuss the identification of a gene expression signature that may distinguish Burkitt's lymphoma from other forms of the disease

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Expression Profile Predicts Best Preoperative Chemotherapy Regimen for Individual Breast Cancer Patients

M.D. Anderson's Lajos Pusztai and Expression Analysis' Tom Goralski discuss using expression data to tailor chemotherapy treatment to individual cancer patients

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New Technique Uses Blood Cells as a ‘Sentinel’ for Diseases Elsewhere in the Body

Michael Burczynski of Wyeth Research and Lisa Lit of the University of California Davis discuss developing methods for examining peripheral blood cell gene expression to monitor diseases

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Scientists Find the Genes that Make Our Internal Clocks Tick

RIKEN CDB's Hiroki Ueda and John Hogenesch of the University of Pennsylvania School of Medicine discuss their methods for discovering temporally expressed genes that regulate the timing of gene expression

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